PEAMT (PEMT) (NM_007169) Human Recombinant Protein
Product Specifications
Background
Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012]
Overview
Recombinant protein of human phosphatidylethanolamine N-methyltransferase (PEMT), nuclear gene encoding mitochondrial protein, transcript variant 2
Synonyms
PEAMT; PEMPT; PEMT2; PLMT; PNMT
Gene ID
10400
UniProt
Q9UBM1
Accession Number mRNA
NM_007169
Chromosomal Location
17p11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Glycerophospholipid metabolism, Metabolic pathways
Field of Research
Glycerophospholipid metabolism, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
22 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PEMT
Species
Human
Protein ID
NP_009100
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10400
Uniprot URL
https://www.uniprot.org/uniprot/Q9UBM1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007169
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_009100
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