XPF (ERCC4) (NM_005236) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6) .[provided by RefSeq, Mar 2009]
Synonyms
ERCC11; FANCQ; RAD1; XFEPS; XPF
Gene ID
2072
UniProt
Q92889, A0A1W1GSK9
Accession Number mRNA
NM_005236
Chromosomal Location
16p13.12
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Nucleotide excision repair
Field of Research
Nucleotide excision repair
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
104.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ERCC4
Species
Human
Protein ID
NP_005227
Overview
Recombinant protein of human excision repair cross-complementing rodent repair deficiency, complementation group 4 (ERCC4)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2072
Uniprot URL
https://www.uniprot.org/uniprot/Q92889
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005236
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005227
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1319073-01 0.02 mg (E-Coli)
Recombinant Arabidopsis thaliana Putative defensin-like protein 263 (At1g68907)
Ask
View Details 
MBS1319073-02 0.1 mg (E-Coli)
Recombinant Arabidopsis thaliana Putative defensin-like protein 263 (At1g68907)
Ask
View Details 
MBS1319073-03 0.02 mg (Yeast)
Recombinant Arabidopsis thaliana Putative defensin-like protein 263 (At1g68907)
Ask
View Details 
MBS1319073-04 0.1 mg (Yeast)
Recombinant Arabidopsis thaliana Putative defensin-like protein 263 (At1g68907)
Ask
View Details MBS1319073-05 0.02 mg (Baculovirus)
Recombinant Arabidopsis thaliana Putative defensin-like protein 263 (At1g68907)
Ask
View Details