TDRD6 (NM_001010870) Human Recombinant Protein

Product Specifications

Background

This gene encodes a tudor domain-containing protein and component of the chromatoid body, a type of ribonucleoprotein granule present in male germ cells. Studies in rodents have demonstrated a role for the encoded protein in spermiogenesis and the nonsense mediated decay (NMD) pathway. This protein is a major autoantigen in human patients with autoimmune polyendocrine syndrome type 1 (APS1) . [provided by RefSeq, Oct 2016]

Overview

Purified recombinant protein of Homo sapiens tudor domain containing 6 (TDRD6)

Synonyms

BA446F17.4; CT41.2; NY-CO-45; SPATA36; TDR2

Gene ID

221400

UniProt

O60522

Accession Number mRNA

NM_001010870

Chromosomal Location

6p12.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

236.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.