TDRD6 (NM_001010870) Human Recombinant Protein
Product Specifications
Background
This gene encodes a tudor domain-containing protein and component of the chromatoid body, a type of ribonucleoprotein granule present in male germ cells. Studies in rodents have demonstrated a role for the encoded protein in spermiogenesis and the nonsense mediated decay (NMD) pathway. This protein is a major autoantigen in human patients with autoimmune polyendocrine syndrome type 1 (APS1) . [provided by RefSeq, Oct 2016]
Overview
Purified recombinant protein of Homo sapiens tudor domain containing 6 (TDRD6)
Synonyms
BA446F17.4; CT41.2; NY-CO-45; SPATA36; TDR2
Gene ID
221400
UniProt
O60522
Accession Number mRNA
NM_001010870
Chromosomal Location
6p12.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
236.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TDRD6
Species
Human
Protein ID
NP_001010870
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/221400
Uniprot URL
https://www.uniprot.org/uniprot/O60522
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001010870
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001010870
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