TBC1D2 (NM_018421) Human Recombinant Protein
Product Specifications
Background
Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human TBC1 domain family, member 2 (TBC1D2)
Synonyms
PARIS-1; PARIS1; TBC1D2A
Gene ID
55357
UniProt
Q9BYX2
Accession Number mRNA
NM_018421
Chromosomal Location
9q22.33
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
103.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TBC1D2
Species
Human
Protein ID
NP_060891
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55357
Uniprot URL
https://www.uniprot.org/uniprot/Q9BYX2
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018421
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060891
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