PUF60 (NM_078480) Human Recombinant Protein
Product Specifications
Background
This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
Synonyms
FIR; RoBPI; SIAHBP1; VRJS
Gene ID
22827
UniProt
Q9UHX1
Accession Number mRNA
NM_078480
Chromosomal Location
8q24.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Spliceosome
Field of Research
Spliceosome
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
2625309529541951
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
59.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PUF60
Species
Human
Protein ID
NP_510965
Overview
Recombinant protein of human poly-U binding splicing factor 60KDa (PUF60), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/22827
Uniprot URL
https://www.uniprot.org/uniprot/Q9UHX1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_078480
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_510965
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7019592-01 0.02 mg
Recombinant Salmonella choleraesuis Putative epimerase lsrE (lsrE)
Ask
View Details 
MBS7019592-02 0.1 mg
Recombinant Salmonella choleraesuis Putative epimerase lsrE (lsrE)
Ask
View Details MBS7019592-03 5x 0.1 mg
Recombinant Salmonella choleraesuis Putative epimerase lsrE (lsrE)
Ask
View Details 46676121 3 x 1.0μg DNA
THSD7A CRISPRa sgRNA lentivector (set of three targets)(Human)
Ask
View Details RC230521L4V 200 µL
RIM1 (RIMS1) (NM_001168410) Human Tagged ORF Clone Lentiviral Particle
Ask
View Details