CERKL (NM_201548) Human Recombinant Protein
Product Specifications
Background
This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD) . Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.[provided by RefSeq, May 2010]
Synonyms
RP26
Gene ID
375298
UniProt
Q49MI3
Accession Number mRNA
NM_201548
Chromosomal Location
2q31.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
59.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CERKL
Species
Human
Protein ID
NP_963842
Overview
Recombinant protein of human ceramide kinase-like (CERKL), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/375298
Uniprot URL
https://www.uniprot.org/uniprot/Q49MI3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_201548
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_963842
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
