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Alanyl tRNA synthetase 2 (AARS2) (NM_020745) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. [provided by RefSeq, Dec 2011]

Overview

Recombinant protein of human alanyl-tRNA synthetase 2, mitochondrial (putative) (AARS2), nuclear gene encoding mitochondrial protein

Synonyms

AARSL; COXPD8; LKENP; MT-ALARS; MTALARS

Gene ID

57505

UniProt

Q5JTZ9

Accession Number mRNA

NM_020745

Chromosomal Location

6p21.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Aminoacyl-tRNA biosynthesis

Field of Research

Aminoacyl-tRNA biosynthesis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

107.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

AARS2

Species

Human

Protein ID

NP_065796

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/57505

Uniprot URL

https://www.uniprot.org/uniprot/Q5JTZ9

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_020745

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_065796

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