Alpha Adducin (ADD1) (NM_001119) Human Recombinant Protein

Product Specifications

Background

Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma) . Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Adducin binds with high affinity to Ca (2+) /calmodulin and is a substrate for protein kinases A and C. [provided by RefSeq, Aug 2017]

Overview

Recombinant protein of human adducin 1 (alpha) (ADD1), transcript variant 1

Synonyms

ADDA

Gene ID

118

UniProt

P35611

Accession Number mRNA

NM_001119

Chromosomal Location

4p16.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

80.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.