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KCTD8 (NM_198353) Human Recombinant Protein

Product Specifications

Background

Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human potassium channel tetramerisation domain containing 8 (KCTD8)

Synonyms

OTTHUMP00000125257; potassium channel tetramerisation domain containing 8

Gene ID

386617

UniProt

Q6ZWB6

Accession Number mRNA

NM_198353

Chromosomal Location

4p13

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

52.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

KCTD8

Species

Human

Protein ID

NP_938167

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/386617

Uniprot URL

https://www.uniprot.org/uniprot/Q6ZWB6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_198353

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_938167

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