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XRN2 (NM_012255) Human Recombinant Protein

Product Specifications

Background

This gene encodes a 5'-3' exonuclease that promotes transcription termination at cotranscriptional cleavage sites. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

Overview

Recombinant protein of human 5'-3' exoribonuclease 2 (XRN2)

Synonyms

5'-3' exoribonuclease 2; Dhm1-like protein (mouse homolog) ; OTTHUMP00000030403

Gene ID

22803

UniProt

Q9H0D6

Accession Number mRNA

NM_012255

Chromosomal Location

20p11.22

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

RNA degradation

Field of Research

RNA degradation

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

108.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

XRN2

Species

Human

Protein ID

NP_036387

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/22803

Uniprot URL

https://www.uniprot.org/uniprot/Q9H0D6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_012255

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_036387

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