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Fmoc-Phe-Lys (Trt) -PAB-PNP

Fmoc-Phe-Lys (Trt) -PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

CAS Number

1116086-09-9

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fmoc-phe-lys-trt-pab-pnp.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

O=C(N)[C@H](CCCCNC(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)N(C([C@H](CC4=CC=CC=C4)NC(OCC5C6=C(C7=C5C=CC=C7)C=CC=C6)=O)=O)C8=CC=C(COC(OC9=CC=C([N+]([O-])=O)C=C9)=O)C=C8

Molecular Formula

C63H57N5O9

Molecular Weight

1028.15

Precautions

H302, H315, H319, H335

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker; Protease Cleavable Linker

Available Sizes

Frequently Asked Questions

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