STK39 (NM_013233) Human Recombinant Protein
Product Specifications
Background
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human serine threonine kinase 39 (STE20/SPS1 homolog, yeast) (STK39)
Synonyms
DCHT; PASK; SPAK
Gene ID
27347
UniProt
Q9UEW8
Accession Number mRNA
NM_013233
Chromosomal Location
2q24.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
59.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
STK39
Species
Human
Protein ID
NP_037365
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/27347
Uniprot URL
https://www.uniprot.org/uniprot/Q9UEW8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013233
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_037365
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