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Peroxiredoxin 5 (PRDX5) (NM_181651) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein interacts with peroxisome receptor 1 and plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites is thought to result in transcript variants that use different in-frame translational start codons to generate isoforms that are targeted to the mitochondrion (isoform L) or peroxisome/cytoplasm (isoform S) . Multiple related pseudogenes have been defined for this gene. [provided by RefSeq, Nov 2017]

Overview

Recombinant protein of human peroxiredoxin 5 (PRDX5), nuclear gene encoding mitochondrial protein, transcript variant 2

Synonyms

ACR1; AOEB166; B166; HEL-S-55; PLP; PMP20; PRDX6; prx-V; PRXV; SBBI10

Gene ID

25824

UniProt

P30044

Accession Number mRNA

NM_181651

Chromosomal Location

11q13.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

17.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PRDX5

Species

Human

Protein ID

NP_857634

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/25824

Uniprot URL

https://www.uniprot.org/uniprot/P30044

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_181651

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_857634

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