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HMGCS1 (NM_001098272) Human Recombinant Protein

Product Specifications

Background

This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.[UniProtKB/Swiss-Prot Function]

Synonyms

HMGCS

Gene ID

3157

UniProt

Q01581, A0A024R059

Accession Number mRNA

NM_001098272

Chromosomal Location

5p12

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Butanoate metabolism, Metabolic pathways, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Valine, leucine and isoleucine degradation

Field of Research

Butanoate metabolism, Metabolic pathways, Synthesis and degradation of ketone bodies, Terpenoid backbone biosynthesis, Valine, leucine and isoleucine degradation

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

57.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

HMGCS1

Species

Human

Protein ID

NP_001091742

Overview

Recombinant protein of human 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) (HMGCS1), transcript variant 1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3157

Uniprot URL

https://www.uniprot.org/uniprot/Q01581

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001098272

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001091742

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