SRGAP2 (NM_015326) Human Recombinant Protein
Product Specifications
Background
This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014]
Synonyms
ARHGAP34; FNBP2; SRGAP2A; SRGAP3
Gene ID
23380
UniProt
O75044, B4DFE5
Accession Number mRNA
NM_015326
Chromosomal Location
1q32.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Axon guidance
Field of Research
Axon guidance
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
120.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SRGAP2
Species
Human
Protein ID
NP_056141
Overview
Recombinant protein of human SLIT-ROBO Rho GTPase activating protein 2 (SRGAP2), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/23380
Uniprot URL
https://www.uniprot.org/uniprot/O75044
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015326
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_056141
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