UNC5C (NM_003728) Human Recombinant Protein
Selected Variant
PH33810M5
Size: 20 µg
Product Specifications
Background
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig) -like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human unc-5 homolog C (C. elegans) (UNC5C)
Synonyms
UNC5H3
Gene ID
8633
UniProt
O95185, A8K385
Accession Number mRNA
NM_003728
Chromosomal Location
4q22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Axon guidance
Field of Research
Axon guidance
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
102.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
UNC5C
Species
Human
Protein ID
NP_003719
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8633
Uniprot URL
https://www.uniprot.org/uniprot/O95185
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003728
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003719
Price
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