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UNC5C (NM_003728) Human Recombinant Protein

Selected Variant

PH33810M5

Size: 20 µg

Product Specifications

Background

This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig) -like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human unc-5 homolog C (C. elegans) (UNC5C)

Synonyms

UNC5H3

Gene ID

8633

UniProt

O95185, A8K385

Accession Number mRNA

NM_003728

Chromosomal Location

4q22.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Axon guidance

Field of Research

Axon guidance

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

102.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

UNC5C

Species

Human

Protein ID

NP_003719

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/8633

Uniprot URL

https://www.uniprot.org/uniprot/O95185

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_003728

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_003719

Price

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