STEAP3 (NM_018234) Human Recombinant Protein

Product Specifications

Background

This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Overview

Recombinant protein of human STEAP family member 3 (STEAP3), transcript variant 2

Synonyms

AHMIO2; dudlin-2; dudulin-2; pHyde; STMP3; TSAP6

Gene ID

55240

UniProt

Q658P3, A1P3F0

Accession Number mRNA

NM_018234

Chromosomal Location

2q14.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

P53 signaling pathway

Field of Research

P53 signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

54.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.