STEAP3 (NM_018234) Human Recombinant Protein
Product Specifications
Background
This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Synonyms
AHMIO2; dudlin-2; dudulin-2; pHyde; STMP3; TSAP6
Gene ID
55240
UniProt
Q658P3, A1P3F0
Accession Number mRNA
NM_018234
Chromosomal Location
2q14.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
P53 signaling pathway
Field of Research
P53 signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
54.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
STEAP3
Species
Human
Protein ID
NP_060704
Overview
Recombinant protein of human STEAP family member 3 (STEAP3), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/55240
Uniprot URL
https://www.uniprot.org/uniprot/Q658P3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_018234
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_060704
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