Sumo 2 (SUMO2) (NM_006937) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Synonyms
HSMT3; Smt3A; SMT3B; SMT3H2; SUMO3
Gene ID
6613
UniProt
P61956, A0A024R8S3
Accession Number mRNA
NM_006937
Chromosomal Location
17q25.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
10.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SUMO2
Species
Human
Protein ID
NP_008868
Overview
Recombinant protein of human SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) (SUMO2), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6613
Uniprot URL
https://www.uniprot.org/uniprot/P61956
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006937
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_008868
Curated Selection
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