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Sumo 2 (SUMO2) (NM_006937) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Synonyms

HSMT3; Smt3A; SMT3B; SMT3H2; SUMO3

Gene ID

6613

UniProt

P61956, A0A024R8S3

Accession Number mRNA

NM_006937

Chromosomal Location

17q25.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

10.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SUMO2

Species

Human

Protein ID

NP_008868

Overview

Recombinant protein of human SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae) (SUMO2), transcript variant 1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/6613

Uniprot URL

https://www.uniprot.org/uniprot/P61956

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_006937

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_008868

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