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PRRG2 (NM_000951) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

Overview

Recombinant protein of human proline rich Gla (G-carboxyglutamic acid) 2 (PRRG2)

Synonyms

PRGP2

Gene ID

5639

UniProt

O14669

Accession Number mRNA

NM_000951

Chromosomal Location

19q13.33

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

22.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PRRG2

Species

Human

Protein ID

NP_000942

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5639

Uniprot URL

https://www.uniprot.org/uniprot/O14669

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000951

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000942

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