ITIH2 (NM_002216) Human Recombinant Protein
Product Specifications
Background
The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 [PubMed 2446322]; Himmelfarb et al., 2004 [PubMed 14744536]) .[supplied by OMIM, Nov 2009]
Overview
Recombinant protein of human inter-alpha (globulin) inhibitor H2 (ITIH2)
Synonyms
H2P; SHAP
Gene ID
3698
UniProt
P19823
Accession Number mRNA
NM_002216
Chromosomal Location
10p14
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
106.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ITIH2
Species
Human
Protein ID
NP_002207
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3698
Uniprot URL
https://www.uniprot.org/uniprot/P19823
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002216
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002207
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