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AK3L1 (AK4) (NM_001005353) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human adenylate kinase 3-like 1 (AK3L1), nuclear gene encoding mitochondrial protein, transcript variant 5

Synonyms

AK3; AK3L1; AK3L2; AK 4

Gene ID

205

UniProt

P27144

Accession Number mRNA

NM_001005353

Chromosomal Location

1p31.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Metabolic pathways, Purine metabolism

Field of Research

Metabolic pathways, Purine metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

25.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

AK4

Species

Human

Protein ID

NP_001005353

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/205

Uniprot URL

https://www.uniprot.org/uniprot/P27144

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001005353

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001005353

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