CSEN (KCNIP3) (NM_001034914) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Synonyms
CSEN; DREAM; KCHIP3
Gene ID
30818
UniProt
Q9Y2W7
Accession Number mRNA
NM_001034914
Chromosomal Location
2q11.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors, Transmembrane
Molecular Weight
26.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KCNIP3
Species
Human
Protein ID
NP_001030086
Overview
Recombinant protein of human Kv channel interacting protein 3, calsenilin (KCNIP3), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/30818
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y2W7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001034914
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001030086
Curated Selection
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