Clathrin light chain (CLTB) (NM_007097) Human Recombinant Protein
Product Specifications
Background
Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Synonyms
LCB
Gene ID
1212
UniProt
P09497
Accession Number mRNA
NM_007097
Chromosomal Location
5q35.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Endocytosis, Huntington's disease, Lysosome
Field of Research
Endocytosis, Huntington's disease, Lysosome
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
25 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CLTB
Species
Human
Protein ID
NP_009028
Overview
Recombinant protein of human clathrin, light chain (Lcb) (CLTB), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1212
Uniprot URL
https://www.uniprot.org/uniprot/P09497
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007097
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_009028
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