Clathrin light chain (CLTB) (NM_007097) Human Recombinant Protein

Product Specifications

Background

Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human clathrin, light chain (Lcb) (CLTB), transcript variant 2

Synonyms

LCB

Gene ID

1212

UniProt

P09497

Accession Number mRNA

NM_007097

Chromosomal Location

5q35.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Endocytosis, Huntington's disease, Lysosome

Field of Research

Endocytosis, Huntington's disease, Lysosome

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

25 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.