CLTCL1 (NM_007098) Human Recombinant Protein

Product Specifications

Background

This gene is a member of the clathrin heavy chain family and encodes a major protein of the polyhedral coat of coated pits and vesicles. Chromosomal aberrations involving this gene are associated with meningioma, DiGeorge syndrome, and velo-cardio-facial syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]

Overview

Recombinant protein of human clathrin, heavy chain-like 1 (CLTCL1)

Synonyms

CHC22; CLH22; CLTCL; CLTD

Gene ID

8218

UniProt

P53675

Accession Number mRNA

NM_007098

Chromosomal Location

22q11.21

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Endocytosis, Huntington's disease, Lysosome

Field of Research

Endocytosis, Huntington's disease, Lysosome

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

186.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.