CD11d (ITGAD) (NM_005353) Human Recombinant Protein
Product Specifications
Background
This gene belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocytes. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Overview
Recombinant protein of human integrin, alpha D (ITGAD)
Synonyms
ADB2; CD11D
Gene ID
3681
UniProt
Q13349, Q59H14
Accession Number mRNA
NM_005353
Chromosomal Location
16p11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Regulation of actin cytoskeleton
Field of Research
Regulation of actin cytoskeleton
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
124.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ITGAD
Species
Human
Protein ID
NP_005344
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3681
Uniprot URL
https://www.uniprot.org/uniprot/Q13349
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005353
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005344
Frequently Asked Questions
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