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SPAG11B (NM_058201) Human Recombinant Protein

Product Specifications

Background

This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human sperm associated antigen 11B (SPAG11B), transcript variant D

Synonyms

EDDM2B; EP2; EP2C; EP2D; HE2; HE2C; SPAG11; SPAG11A

Gene ID

10407

UniProt

Q08648

Accession Number mRNA

NM_058201

Chromosomal Location

8p23.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein

Molecular Weight

12.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SPAG11B

Species

Human

Protein ID

NP_478108

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/10407

Uniprot URL

https://www.uniprot.org/uniprot/Q08648

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_058201

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_478108

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