SCP1 (SYCP1) (NM_003176) Human Recombinant Protein
Product Specifications
Background
Major component of the transverse filaments of synaptonemal complexes, formed between homologous chromosomes during meiotic prophase. Required for normal assembly of the central element of the synaptonemal complexes. Required for normal centromere pairing during meiosis. Required for normal meiotic chromosome synapsis during oocyte and spermatocyte development and for normal male and female fertility.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human synaptonemal complex protein 1 (SYCP1)
Synonyms
CT8; HOM-TES-14; SCP-1; SCP1
Gene ID
6847
UniProt
Q15431, A0A024R0I2
Accession Number mRNA
NM_003176
Chromosomal Location
1p13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
114 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SYCP1
Species
Human
Protein ID
NP_003167
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6847
Uniprot URL
https://www.uniprot.org/uniprot/Q15431
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003176
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003167
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