SH3MD2 (SH3RF1) (NM_020870) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. [provided by RefSeq, Jul 2008]
Synonyms
POSH; RNF142; SH3MD2
Gene ID
57630
UniProt
Q7Z6J0
Accession Number mRNA
NM_020870
Chromosomal Location
4q32.3-q33
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
92.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SH3RF1
Species
Human
Protein ID
NP_065921
Overview
Recombinant protein of human SH3 domain containing ring finger 1 (SH3RF1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/57630
Uniprot URL
https://www.uniprot.org/uniprot/Q7Z6J0
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_020870
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_065921
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