INCA (CARD17) (NM_001007232) Human Recombinant Protein
Product Specifications
Background
Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human caspase recruitment domain family, member 17 (CARD17)
Synonyms
INCA
Gene ID
440068
UniProt
Q5XLA6
Accession Number mRNA
NM_001007232
Chromosomal Location
11q22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
11.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CARD17
Species
Human
Protein ID
NP_001007233
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/440068
Uniprot URL
https://www.uniprot.org/uniprot/Q5XLA6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001007232
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001007233
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