Insulin Receptor R (INSRR) (NM_014215) Human Recombinant Protein
Product Specifications
Background
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human insulin receptor-related receptor (INSRR)
Synonyms
IRR
Gene ID
3645
UniProt
P14616
Accession Number mRNA
NM_014215
Chromosomal Location
1q23.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Prostate cancer, Regulation of actin cytoskeleton
Field of Research
Prostate cancer, Regulation of actin cytoskeleton
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase, Transmembrane
Molecular Weight
140.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
INSRR
Species
Human
Protein ID
NP_055030
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3645
Uniprot URL
https://www.uniprot.org/uniprot/P14616
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014215
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055030
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