MARS2 (NM_138395) Human Recombinant Protein
Product Specifications
Background
This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3) . [provided by RefSeq, Apr 2014]
Overview
Recombinant protein of human methionyl-tRNA synthetase 2, mitochondrial (MARS2), nuclear gene encoding mitochondrial protein
Synonyms
COXPD25; MetRS; mtMetRS
Gene ID
92935
UniProt
Q96GW9
Accession Number mRNA
NM_138395
Chromosomal Location
2q33.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Aminoacyl-tRNA biosynthesis, Selenoamino acid metabolism
Field of Research
Aminoacyl-tRNA biosynthesis, Selenoamino acid metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
64.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MARS2
Species
Human
Protein ID
NP_612404
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/92935
Uniprot URL
https://www.uniprot.org/uniprot/Q96GW9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_138395
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_612404
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