YPEL5 (NM_001127401) Human Recombinant Protein
Product Specifications
Background
Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (PubMed:29911972) . Required for normal cell proliferation (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Homo sapiens yippee-like 5 (Drosophila) (YPEL5), transcript variant 1
Synonyms
CGI-127
Gene ID
51646
UniProt
P62699
Accession Number mRNA
NM_001127401
Chromosomal Location
2p23.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
13.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
YPEL5
Species
Human
Protein ID
NP_001120873
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51646
Uniprot URL
https://www.uniprot.org/uniprot/P62699
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001127401
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001120873
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