FKBP2 (NM_001135208) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
Synonyms
FKBP-13; FKBP13; PPIase
Gene ID
2286
UniProt
P26885, Q53XJ5
Accession Number mRNA
NM_001135208
Chromosomal Location
11q13.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
13.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FKBP2
Species
Human
Protein ID
NP_001128680
Overview
Recombinant protein of human FK506 binding protein 2, 13kDa (FKBP2), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2286
Uniprot URL
https://www.uniprot.org/uniprot/P26885
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001135208
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001128680
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