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EEF1D (NM_001130055) Human Recombinant Protein

Product Specifications

Background

This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided by RefSeq, Aug 2010]

Overview

Recombinant protein of human eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) (EEF1D), transcript variant 5

Synonyms

EF-1D; EF1D; FP1047

Gene ID

1936

UniProt

P29692

Accession Number mRNA

NM_001130055

Chromosomal Location

8q24.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

30.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EEF1D

Species

Human

Protein ID

NP_001123527

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/1936

Uniprot URL

https://www.uniprot.org/uniprot/P29692

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001130055

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001123527

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