Heme oxygenase 2 (HMOX2) (NM_001127206) Human Recombinant Protein
Product Specifications
Background
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
Synonyms
HO-2
Gene ID
3163
UniProt
P30519
Accession Number mRNA
NM_001127206
Chromosomal Location
16p13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Porphyrin and chlorophyll metabolism
Field of Research
Porphyrin and chlorophyll metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
35.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
HMOX2
Species
Human
Protein ID
NP_001120678
Overview
Purified recombinant protein of Homo sapiens heme oxygenase (decycling) 2 (HMOX2), transcript variant 4
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3163
Uniprot URL
https://www.uniprot.org/uniprot/P30519
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001127206
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001120678
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