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FBP1 (NM_001127628) Human Recombinant Protein

Product Specifications

Background

Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human fructose-1, 6-bisphosphatase 1 (FBP1), transcript variant 2

Synonyms

FBP

Gene ID

2203

UniProt

P09467, Q2TU34

Accession Number mRNA

NM_001127628

Chromosomal Location

9q22.32

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Pentose phosphate pathway

Field of Research

Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Pentose phosphate pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Stem cell - Pluripotency

Molecular Weight

36.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FBP1

Species

Human

Protein ID

NP_001121100

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2203

Uniprot URL

https://www.uniprot.org/uniprot/P09467

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001127628

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001121100

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