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BAAT (NM_001127610) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA) . Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Synonyms

BACAT; BACD1; BAT; HCHO

Gene ID

570

UniProt

Q14032

Accession Number mRNA

NM_001127610

Chromosomal Location

9q31.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Biosynthesis of unsaturated fatty acids, Metabolic pathways, Primary bile acid biosynthesis, Taurine and hypotaurine metabolism

Field of Research

Biosynthesis of unsaturated fatty acids, Metabolic pathways, Primary bile acid biosynthesis, Taurine and hypotaurine metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

46.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

BAAT

Species

Human

Protein ID

NP_001121082

Overview

Recombinant protein of human bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) (BAAT), transcript variant 2

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/570

Uniprot URL

https://www.uniprot.org/uniprot/Q14032

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001127610

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001121082

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