ATF7 (NM_001130059) Human Recombinant Protein
Product Specifications
Background
Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Homo sapiens activating transcription factor 7 (ATF7), transcript variant 1
Synonyms
ATFA
Gene ID
11016
UniProt
P17544
Accession Number mRNA
NM_001130059
Chromosomal Location
12q13.13
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
52.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ATF7
Species
Human
Protein ID
NP_001123531
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11016
Uniprot URL
https://www.uniprot.org/uniprot/P17544
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001130059
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001123531
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