Eph receptor A7 (EPHA7) (NM_004440) Human Recombinant Protein
Product Specifications
Background
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Synonyms
EHK-3; EHK3; EK11; HEK11
Gene ID
2045
UniProt
Q15375
Accession Number mRNA
NM_004440
Chromosomal Location
6q16.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Axon guidance
Field of Research
Axon guidance
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase, Transmembrane
Molecular Weight
111.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EPHA7
Species
Human
Protein ID
NP_004431
Overview
Recombinant protein of human EPH receptor A7 (EPHA7)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2045
Uniprot URL
https://www.uniprot.org/uniprot/Q15375
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004440
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004431
Curated Selection
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