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Eph receptor A7 (EPHA7) (NM_004440) Human Recombinant Protein

Product Specifications

Background

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Overview

Recombinant protein of human EPH receptor A7 (EPHA7)

Synonyms

EHK-3; EHK3; EK11; HEK11

Gene ID

2045

UniProt

Q15375

Accession Number mRNA

NM_004440

Chromosomal Location

6q16.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Axon guidance

Field of Research

Axon guidance

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase, Transmembrane

Molecular Weight

111.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EPHA7

Species

Human

Protein ID

NP_004431

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2045

Uniprot URL

https://www.uniprot.org/uniprot/Q15375

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004440

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004431

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