ROBO2 (NM_001128929) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Overview
Recombinant protein of human roundabout, axon guidance receptor, homolog 2 (Drosophila) (ROBO2), transcript variant 1
Synonyms
SAX3
Gene ID
6092
UniProt
Q9HCK4
Accession Number mRNA
NM_001128929
Chromosomal Location
3p12.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Axon guidance
Field of Research
Axon guidance
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
152.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ROBO2
Species
Human
Protein ID
NP_001122401
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6092
Uniprot URL
https://www.uniprot.org/uniprot/Q9HCK4
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001128929
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001122401
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC400029-500 1x 500 µL
Fibronectin (TV-1), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740528-500 1x 500 µL
ZAP70 (ZAP70/528), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC472980-500 1x 500 µL
MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) (MUC1/2980R), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC942276-100 1x 100 µL
CD52 (Epididymis-Specific Protein 5) (CD52/2276R), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details