BCOR (NM_001123383) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.[provided by RefSeq, Jun 2010]
Synonyms
ANOP2; MAA2; MCOPS2
Gene ID
54880
UniProt
Q6W2J9
Accession Number mRNA
NM_001123383
Chromosomal Location
Xp11.4
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
188 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
BCOR
Species
Human
Protein ID
NP_001116855
Overview
Recombinant protein of human BCL6 co-repressor (BCOR), transcript variant 3
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/54880
Uniprot URL
https://www.uniprot.org/uniprot/Q6W2J9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001123383
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001116855
Curated Selection
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