NONO (NM_001145409) Human Recombinant Protein
Product Specifications
Background
This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16. [provided by RefSeq, Feb 2009]
Overview
Recombinant protein of human non-POU domain containing, octamer-binding (NONO), transcript variant 3
Synonyms
MRXS34; NMT55; NRB54; P54; P54NRB; PPP1R114
Gene ID
4841
UniProt
Q15233, A0A0S2Z4Z9
Accession Number mRNA
NM_001145409
Chromosomal Location
Xq13.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
54.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NONO
Species
Human
Protein ID
NP_001138881
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4841
Uniprot URL
https://www.uniprot.org/uniprot/Q15233
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001145409
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001138881
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