KCTD1 (NM_001136205) Human Recombinant Protein
Selected Variant
PH33393M5
Size: 20 µg
Product Specifications
Background
This gene encodes a protein containing a BTB (Broad-complex, tramtrack and bric a brac), also known as a POZ (POxvirus and zinc finger) protein-protein interaction domain. The encoded protein negatively regulates the AP-2 family of transcription factors and the Wnt signaling pathway. A mechanism for the modulation of Wnt signaling has been proposed in which the encoded protein enhances ubiquitination and degradation of the beta-catenin protein. Mutations in this gene have been identified in Scalp-ear-nipple (SEN) syndrome. [provided by RefSeq, May 2017]
Overview
Recombinant protein of human potassium channel tetramerisation domain containing 1 (KCTD1), transcript variant 1
Synonyms
C18orf5
Gene ID
284252
UniProt
Q719H9, A0A024RC45
Accession Number mRNA
NM_001136205
Chromosomal Location
18q11.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Ion Channels: Other
Molecular Weight
29.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
KCTD1
Species
Human
Protein ID
NP_001129677
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/284252
Uniprot URL
https://www.uniprot.org/uniprot/Q719H9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001136205
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001129677
Price
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