Guaifenesin-d5

Guaifenesin-d5 is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough. Guaifenesin also has narcotic effect[1][2].

Product Specifications

CAS Number

[1329563-41-8]

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Solubility

10 mM in DMSO

Smiles

O(C(C(C(O)([2H])[2H])(O)[2H])([2H])[2H])C1=C(OC)C=CC=C1

Molecular Formula

C10H9D5O4

Molecular Weight

203.25

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Bennett, S., N. Hoffman, and M. Monga, Ephedrine- and guaifenesin-induced nephrolithiasis. J Altern Complement Med, 2004. 10 (6) : p. 967-9.|[3]Dicpinigaitis PV, et, al. Effect of guaifenesin on cough reflex sensitivity. Chest. 2003 Dec;124 (6) :2178-81.