GPR56 (ADGRG1) (NM_001145771) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Overview
Recombinant protein of human G protein-coupled receptor 56 (GPR56), transcript variant 4
Synonyms
BFPP; BPPR; GPR56; TM7LN4; TM7XN1
Gene ID
9289
UniProt
Q9Y653, A0A024R6U7
Accession Number mRNA
NM_001145771
Chromosomal Location
16q21
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, GPCR, Transmembrane
Molecular Weight
75 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ADGRG1
Species
Human
Protein ID
NP_001139243
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9289
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y653
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001145771
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001139243
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