Synaptotagmin 1 (SYT1) (NM_001135805) Human Recombinant Protein
Product Specifications
Background
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca (2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse (Fernandez-Chacon et al., 2001 [PubMed 11242035]) .[supplied by OMIM, Jul 2010]
Synonyms
BAGOS; P65; SVP65; SYT
Gene ID
6857
UniProt
P21579, A0A024RBE9
Accession Number mRNA
NM_001135805
Chromosomal Location
12q21.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein, Transmembrane
Molecular Weight
47.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SYT1
Species
Human
Protein ID
NP_001129277
Overview
Recombinant protein of human synaptotagmin I (SYT1), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6857
Uniprot URL
https://www.uniprot.org/uniprot/P21579
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001135805
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001129277
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