EDC3 (NM_001142444) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability. [provided by RefSeq, May 2017]

Overview

Recombinant protein of human enhancer of mRNA decapping 3 homolog (S. cerevisiae) (EDC3), transcript variant 2

Synonyms

HYjeF_N2-15q23; LSM16; MRT50; YJDC; YJEFN2

Gene ID

80153

UniProt

Q96F86

Accession Number mRNA

NM_001142444

Chromosomal Location

15q24.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

RNA degradation

Field of Research

RNA degradation

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

55.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.