EDC3 (NM_001142444) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that is important in mRNA degradation. The encoded protein is a component of a decapping complex that promotes efficient removal of the monomethylguanosine (m7G) cap from mRNAs, as part of the 5' to 3' mRNA decay pathway. Mutations in this gene have been identified in human patients with an autosomal recessive form of intellectual disability. [provided by RefSeq, May 2017]
Synonyms
HYjeF_N2-15q23; LSM16; MRT50; YJDC; YJEFN2
Gene ID
80153
UniProt
Q96F86
Accession Number mRNA
NM_001142444
Chromosomal Location
15q24.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
RNA degradation
Field of Research
RNA degradation
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
55.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EDC3
Species
Human
Protein ID
NP_001135916
Overview
Recombinant protein of human enhancer of mRNA decapping 3 homolog (S. cerevisiae) (EDC3), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/80153
Uniprot URL
https://www.uniprot.org/uniprot/Q96F86
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001142444
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001135916
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