ITPK1 (NM_001142593) Human Recombinant Protein

Product Specifications

Background

This gene encodes an enzyme that belongs to the inositol 1,3,4-trisphosphate 5/6-kinase family. This enzyme regulates the synthesis of inositol tetraphosphate, and downstream products, inositol pentakisphosphate and inositol hexakisphosphate. Inositol metabolism plays a role in the development of the neural tube. Disruptions in this gene are thought to be associated with neural tube defects. A pseudogene of this gene has been identified on chromosome X. [provided by RefSeq, Jul 2016]

Overview

Recombinant protein of human inositol 1, 3, 4-triphosphate 5/6 kinase (ITPK1), transcript variant 2

Synonyms

ITRPK1

Gene ID

3705

UniProt

Q13572, A0A024R6H3

Accession Number mRNA

NM_001142593

Chromosomal Location

14q32.12

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system

Field of Research

Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

45.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.