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FGF1 (NM_001144892) Human Recombinant Protein

Selected Variant

PH33309M5

Size: 20 µg

Product Specifications

Background

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]

Overview

Purified recombinant protein of Homo sapiens fibroblast growth factor 1 (acidic) (FGF1), transcript variant 4

Synonyms

AFGF; ECGF; ECGF-beta; ECGFA; ECGFB; FGF-1; FGF-alpha; FGFA; GLIO703; HBGF-1; HBGF1

Gene ID

2246

UniProt

P05230

Accession Number mRNA

NM_001144892

Chromosomal Location

5q31.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

Field of Research

MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Secreted Protein

Molecular Weight

17.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FGF1

Species

Human

Protein ID

NP_001138364

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2246

Uniprot URL

https://www.uniprot.org/uniprot/P05230

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001144892

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001138364

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